LITESEC-T3SS - Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution

The type III secretion system (T3SS) of bacteria can be used to inject cargo into eukaryotic cells but its lack of target specificity is a disadvantage. Here the authors place the T3SS under the regulation of light by engineering optogenetic switches into the dynamic cytosolic T3SS component SctQ.

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Autores principales: Florian Lindner, Bailey Milne-Davies, Katja Langenfeld, Thorsten Stiewe, Andreas Diepold
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/d6971f55f08f4ba59594684ea20501bc
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