Restoration of the healing microenvironment in diabetic wounds with matrix-binding IL-1 receptor antagonist

Tan, Lash et al. show that blocking the Interleukin-1 receptor promotes rapid wound closure in diabetic mice. They engineered a matrix binding form of Interleukin-1 receptor antagonist (IL-1Ra) that has the ability of precise localisation and retention in the tissue. IL-1Ra holds the potential for e...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jean L. Tan, Blake Lash, Rezvan Karami, Bhavana Nayer, Yen-Zhen Lu, Celeste Piotto, Ziad Julier, Mikaël M. Martino
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Accès en ligne:https://doaj.org/article/d69e7e9bda4641d3aec93935b49ff999
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!