Prediction of protein binding regions in disordered proteins.

Many disordered proteins function via binding to a structured partner and undergo a disorder-to-order transition. The coupled folding and binding can confer several functional advantages such as the precise control of binding specificity without increased affinity. Additionally, the inherent flexibi...

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Auteurs principaux: Bálint Mészáros, István Simon, Zsuzsanna Dosztányi
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/d6acbe0e3afb4baca57062bf2b6689bd
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