Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization

Cell senescence involves stable arrest of cell proliferation and changes in gene expression and 3D genome reorganization. Here, the authors show that human condensin II complex participates in reorganization of the chromatin compartments, primarily through switching from heterochromatic B to euchrom...

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Autores principales:	Osamu Iwasaki, Hideki Tanizawa, Kyoung-Dong Kim, Andrew Kossenkov, Timothy Nacarelli, Sanki Tashiro, Sonali Majumdar, Louise C. Showe, Rugang Zhang, Ken-ichi Noma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d6bfd9f78d8e46fe944d870a5010386b
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spelling	oai:doaj.org-article:d6bfd9f78d8e46fe944d870a5010386b2021-12-02T15:35:33ZInvolvement of condensin in cellular senescence through gene regulation and compartmental reorganization10.1038/s41467-019-13604-52041-1723https://doaj.org/article/d6bfd9f78d8e46fe944d870a5010386b2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13604-5https://doaj.org/toc/2041-1723Cell senescence involves stable arrest of cell proliferation and changes in gene expression and 3D genome reorganization. Here, the authors show that human condensin II complex participates in reorganization of the chromatin compartments, primarily through switching from heterochromatic B to euchromatic A compartments.Osamu IwasakiHideki TanizawaKyoung-Dong KimAndrew KossenkovTimothy NacarelliSanki TashiroSonali MajumdarLouise C. ShoweRugang ZhangKen-ichi NomaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-20 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Osamu Iwasaki Hideki Tanizawa Kyoung-Dong Kim Andrew Kossenkov Timothy Nacarelli Sanki Tashiro Sonali Majumdar Louise C. Showe Rugang Zhang Ken-ichi Noma Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
description	Cell senescence involves stable arrest of cell proliferation and changes in gene expression and 3D genome reorganization. Here, the authors show that human condensin II complex participates in reorganization of the chromatin compartments, primarily through switching from heterochromatic B to euchromatic A compartments.
format	article
author	Osamu Iwasaki Hideki Tanizawa Kyoung-Dong Kim Andrew Kossenkov Timothy Nacarelli Sanki Tashiro Sonali Majumdar Louise C. Showe Rugang Zhang Ken-ichi Noma
author_facet	Osamu Iwasaki Hideki Tanizawa Kyoung-Dong Kim Andrew Kossenkov Timothy Nacarelli Sanki Tashiro Sonali Majumdar Louise C. Showe Rugang Zhang Ken-ichi Noma
author_sort	Osamu Iwasaki
title	Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
title_short	Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
title_full	Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
title_fullStr	Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
title_full_unstemmed	Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
title_sort	involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d6bfd9f78d8e46fe944d870a5010386b
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Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization

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