<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

<named-content content-type="genus-species">Cryptococcus neoformans</named-content> Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

ABSTRACT Chitin is an essential component of the cell wall of Cryptococcus neoformans conferring structural rigidity and integrity under diverse environmental conditions. Chitin deacetylase genes encode the enyzmes (chitin deacetylases [Cdas]) that deacetylate chitin, converting it to chitosan. The...

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Bibliographic Details
Main Authors: Rajendra Upadhya, Lorina G. Baker, Woei C. Lam, Charles A. Specht, Maureen J. Donlin, Jennifer K. Lodge
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
chitin deacetylase
catalytic site
cell wall localization
chitosan
metal binding site
fungal virulence
Microbiology
QR1-502
Online Access:https://doaj.org/article/d6e613ec492c4b0b8e3f5e22fe269e90
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