MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing
Aberrant alternative splicing has been shown to contribute to the tumorigenic processes. Here, the authors show that MTR4 is overexpressed in hepatocellular carcinoma and has a role in tumorigenesis through the modulation of the splicing of glycolytic genes PKM2 and GLUT1.
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/d6f7056973d7420fa80b0b12ab8c2f6e |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|