Linking System-Wide Impacts of RNA Polymerase Mutations to the Fitness Cost of Rifampin Resistance in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>

ABSTRACT Fitness costs play a key role in the evolutionary dynamics of antibiotic resistance in bacteria by generating selection against resistance in the absence of antibiotics. Although the genetic basis of antibiotic resistance is well understood, the precise molecular mechanisms linking the gene...

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Autores principales: Qin Qi, Gail M. Preston, R. Craig MacLean
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/d6f8f69b1fba4c6a8098ccf75de983fa
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