HIV-1 Vpu Promotes Phagocytosis of Infected CD4<sup>+</sup> T Cells by Macrophages through Downregulation of CD47

ABSTRACT Human immunodeficiency virus (HIV) remodels the cell surface of infected cells to facilitate viral dissemination and promote immune evasion. The membrane-associated viral protein U (Vpu) accessory protein encoded by HIV-1 plays a key role in this process by altering cell surface levels of m...

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Bibliographic Details
Main Authors: Lijun Cong, Scott M. Sugden, Pascal Leclair, Chinten James Lim, Tram N. Q. Pham, Éric A. Cohen
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
HIV
Vpu
Online Access:https://doaj.org/article/d6fdd7d783664074913626708b92d350
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