Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes.

The Y chromosome harbors nine multi-copy ampliconic gene families expressed exclusively in testis. The gene copies within each family are >99% identical to each other, which poses a major challenge in evaluating their copy number. Recent studies demonstrated high variation in Y ampliconic gene co...

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Autores principales: Rahulsimham Vegesna, Marta Tomaszkiewicz, Paul Medvedev, Kateryna D Makova
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2019
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Acceso en línea:https://doaj.org/article/d7079b7d3d444c228813a9406c290bc1
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