Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes.
The Y chromosome harbors nine multi-copy ampliconic gene families expressed exclusively in testis. The gene copies within each family are >99% identical to each other, which poses a major challenge in evaluating their copy number. Recent studies demonstrated high variation in Y ampliconic gene co...
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Autores principales: | Rahulsimham Vegesna, Marta Tomaszkiewicz, Paul Medvedev, Kateryna D Makova |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/d7079b7d3d444c228813a9406c290bc1 |
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