Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for <italic toggle="yes">In Vivo</italic> Protection in a Serum Transfer Mouse Challenge Model

ABSTRACT The immunogenicity of current influenza virus vaccines is assessed by measuring an increase of influenza virus-specific antibodies in a hemagglutination inhibition assay. This method exclusively measures antibodies against the hemagglutinin head domain. While this domain is immunodominant,...

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Autores principales:	Henning Jacobsen, Madhusudan Rajendran, Angela Choi, Haakon Sjursen, Karl A. Brokstad, Rebecca J. Cox, Peter Palese, Florian Krammer, Raffael Nachbagauer
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2017
Materias:	ADCC ELISA correlate of protection hemagglutinin hemagglutinin stalk influenza Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/d709eec0ace54c98a0b1c220de07b37d
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Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for <italic toggle="yes">In Vivo</italic> Protection in a Serum Transfer Mouse Challenge Model

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