Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae

Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae

PcActx peptide, identified from the transcriptome of zoantharian Palythoa caribaeorum, was clustered into the phylogeny of analgesic polypeptides from sea anemone Heteractis crispa (known as APHC peptides). APHC peptides were considered as inhibitors of transient receptor potential cation channel su...

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Autores principales: Xiufen Wang, Qiwen Liao, Hanbin Chen, Guiyi Gong, Shirley Weng In Siu, Qian Chen, Hiotong Kam, Carolina Oi Lam Ung, Kwok-Kuen Cheung, Gandhi Rádis-Baptista, Clarence Tsun Ting Wong, Simon Ming-Yuen Lee
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
zoantharian
PcActx peptide
transcriptomics analysis
TRPV1 channel
anti-epilepsy
zebrafish
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/d7319914ec294906b2ff256da5e334e6
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https://doaj.org/article/d7319914ec294906b2ff256da5e334e6

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