LigD: A Structural Guide to the Multi-Tool of Bacterial Non-Homologous End Joining

DNA double-strand breaks are the most lethal form of damage for living organisms. The non-homologous end joining (NHEJ) pathway can repair these breaks without the use of a DNA template, making it a critical repair mechanism when DNA is not replicating, but also a threat to genome integrity. NHEJ re...

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Autores principales: Benhur Amare, Anthea Mo, Noorisah Khan, Dana J. Sowa, Monica M. Warner, Andriana Tetenych, Sara N. Andres
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/d73893c5acb64be99a63598409687c0d
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