Hypoxia: The Cornerstone of Glioblastoma

Glioblastoma is the most aggressive form of brain tumor in adults and is characterized by the presence of hypervascularization and necrosis, both caused by a hypoxic microenvironment. In this review, we highlight that hypoxia-induced factor 1 (HIF-1), the main factor activated by hypoxia, is an impo...

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Autores principales: Marta Domènech, Ainhoa Hernández, Andrea Plaja, Eva Martínez-Balibrea, Carmen Balañà
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/d74eba75d08d4042af97cc5a900b3566
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