Hypoxia: The Cornerstone of Glioblastoma
Glioblastoma is the most aggressive form of brain tumor in adults and is characterized by the presence of hypervascularization and necrosis, both caused by a hypoxic microenvironment. In this review, we highlight that hypoxia-induced factor 1 (HIF-1), the main factor activated by hypoxia, is an impo...
Guardado en:
Autores principales: | Marta Domènech, Ainhoa Hernández, Andrea Plaja, Eva Martínez-Balibrea, Carmen Balañà |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d74eba75d08d4042af97cc5a900b3566 |
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