Conformational switching in the coiled-coil domains of a proteasomal ATPase regulates substrate processing

Proteasomal ATPases contain functionally important coiled-coil (CC) domains, the mechanistic role of which is not fully understood. Here, the authors provide evidence for three distinct CC conformations, showing that CC conformational changes enable ATPases to switch between active and resting state...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Aaron Snoberger, Evan J. Brettrager, David M. Smith
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/d753a210f94644cf8f78d72fae386d53
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!