The Zebrafish Antiapoptotic Protein BIRC2 Promotes Edwardsiella piscicida Infection by Inhibiting Caspases and Accumulating p53 in a p53 Transcription-Dependent and -Independent Manner

IAPs (inhibitors of apoptosis) are endogenous caspase inhibitors with multiple biological activities. In the present study, we show functional characteristics of antiapoptotic protein BIRC2 (cIAP1) in response to Edwardsiella piscicida infection. Overexpression of BIRC2 in zebrafish larvae promoted...

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Autores principales: Lu Cao, Dong Yan, Jun Xiao, Hao Feng, Ming Xian Chang
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
p53
Acceso en línea:https://doaj.org/article/d75e20c2ee5040f0818dfa8116b2fa52
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