The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.
Heme is a ligand for the human nuclear receptors (NR) REV-ERBalpha and REV-ERBbeta, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and diseases such as diabetes, atherosclerosis, inflammation, and cancer. Here we show that transcript...
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| Auteurs principaux: | , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2009
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| Accès en ligne: | https://doaj.org/article/d76afef7ed9440828f6f21f6b78d7b15 |
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