Split Intein-Mediated Protein Ligation for detecting protein-protein interactions and their inhibition

Protein-protein interactions are fundamental to the regulation of protein activity and cellular phyisology. Here the authors present Split Intein-Mediated Protein Ligation, which uses bait and prey proteins fused to intein fragments to generate single intact proteins upon interaction.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhong Yao, Farzaneh Aboualizadeh, Jason Kroll, Indira Akula, Jamie Snider, Anna Lyakisheva, Priscilla Tang, Max Kotlyar, Igor Jurisica, Mike Boxem, Igor Stagljar
Format: article
Langue:EN
Publié: Nature Portfolio 2020
Sujets:
Q
Accès en ligne:https://doaj.org/article/d7c200701845452a9c8b0403041b6f6f
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!