Genetic variants of calcium and vitamin D metabolism in kidney stone disease

Genetic variants of calcium and vitamin D metabolism in kidney stone disease

Kidney stones form in the presence of overabundance of crystal-forming substances such as Ca2+ and oxalate. Here, the authors report genome-wide association analyses for kidney stone disease, report seven previously unknown loci and find that some of these loci also associate with Ca2+ concentration...

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Bibliographic Details
Main Authors: Sarah A. Howles, Akira Wiberg, Michelle Goldsworthy, Asha L. Bayliss, Anna K. Gluck, Michael Ng, Emily Grout, Chizu Tanikawa, Yoichiro Kamatani, Chikashi Terao, Atsushi Takahashi, Michiaki Kubo, Koichi Matsuda, Rajesh V. Thakker, Benjamin W. Turney, Dominic Furniss
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
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Online Access:https://doaj.org/article/d7ce612d6257411d94aa0d789886d3f0
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https://doaj.org/article/d7ce612d6257411d94aa0d789886d3f0

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