Genetic variants of calcium and vitamin D metabolism in kidney stone disease

Kidney stones form in the presence of overabundance of crystal-forming substances such as Ca2+ and oxalate. Here, the authors report genome-wide association analyses for kidney stone disease, report seven previously unknown loci and find that some of these loci also associate with Ca2+ concentration...

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Autores principales:	Sarah A. Howles, Akira Wiberg, Michelle Goldsworthy, Asha L. Bayliss, Anna K. Gluck, Michael Ng, Emily Grout, Chizu Tanikawa, Yoichiro Kamatani, Chikashi Terao, Atsushi Takahashi, Michiaki Kubo, Koichi Matsuda, Rajesh V. Thakker, Benjamin W. Turney, Dominic Furniss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d7ce612d6257411d94aa0d789886d3f0
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spelling	oai:doaj.org-article:d7ce612d6257411d94aa0d789886d3f02021-12-02T15:35:35ZGenetic variants of calcium and vitamin D metabolism in kidney stone disease10.1038/s41467-019-13145-x2041-1723https://doaj.org/article/d7ce612d6257411d94aa0d789886d3f02019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13145-xhttps://doaj.org/toc/2041-1723Kidney stones form in the presence of overabundance of crystal-forming substances such as Ca2+ and oxalate. Here, the authors report genome-wide association analyses for kidney stone disease, report seven previously unknown loci and find that some of these loci also associate with Ca2+ concentration and excretion.Sarah A. HowlesAkira WibergMichelle GoldsworthyAsha L. BaylissAnna K. GluckMichael NgEmily GroutChizu TanikawaYoichiro KamataniChikashi TeraoAtsushi TakahashiMichiaki KuboKoichi MatsudaRajesh V. ThakkerBenjamin W. TurneyDominic FurnissNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sarah A. Howles Akira Wiberg Michelle Goldsworthy Asha L. Bayliss Anna K. Gluck Michael Ng Emily Grout Chizu Tanikawa Yoichiro Kamatani Chikashi Terao Atsushi Takahashi Michiaki Kubo Koichi Matsuda Rajesh V. Thakker Benjamin W. Turney Dominic Furniss Genetic variants of calcium and vitamin D metabolism in kidney stone disease
description	Kidney stones form in the presence of overabundance of crystal-forming substances such as Ca2+ and oxalate. Here, the authors report genome-wide association analyses for kidney stone disease, report seven previously unknown loci and find that some of these loci also associate with Ca2+ concentration and excretion.
format	article
author	Sarah A. Howles Akira Wiberg Michelle Goldsworthy Asha L. Bayliss Anna K. Gluck Michael Ng Emily Grout Chizu Tanikawa Yoichiro Kamatani Chikashi Terao Atsushi Takahashi Michiaki Kubo Koichi Matsuda Rajesh V. Thakker Benjamin W. Turney Dominic Furniss
author_facet	Sarah A. Howles Akira Wiberg Michelle Goldsworthy Asha L. Bayliss Anna K. Gluck Michael Ng Emily Grout Chizu Tanikawa Yoichiro Kamatani Chikashi Terao Atsushi Takahashi Michiaki Kubo Koichi Matsuda Rajesh V. Thakker Benjamin W. Turney Dominic Furniss
author_sort	Sarah A. Howles
title	Genetic variants of calcium and vitamin D metabolism in kidney stone disease
title_short	Genetic variants of calcium and vitamin D metabolism in kidney stone disease
title_full	Genetic variants of calcium and vitamin D metabolism in kidney stone disease
title_fullStr	Genetic variants of calcium and vitamin D metabolism in kidney stone disease
title_full_unstemmed	Genetic variants of calcium and vitamin D metabolism in kidney stone disease
title_sort	genetic variants of calcium and vitamin d metabolism in kidney stone disease
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d7ce612d6257411d94aa0d789886d3f0
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Genetic variants of calcium and vitamin D metabolism in kidney stone disease

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