Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA
Abstract The nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2021
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Acceso en línea: | https://doaj.org/article/d7d7351fa7fa4902828aa877384f06ac |
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