Fluorescent thermal shift-based method for detection of NF-κB binding to double-stranded DNA
Abstract The nuclear factor kappa B (NF-κB) family of dimeric transcription factors regulates a wide range of genes by binding to their specific DNA regulatory sequences. NF-κB is an important therapeutic target linked to a number of cancers as well as autoimmune and inflammatory diseases. Therefore...
Guardado en:
Autores principales: | Peter D. Leitner, Ilja Vietor, Lukas A. Huber, Taras Valovka |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d7d7351fa7fa4902828aa877384f06ac |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Double-stranded RNA induces chicken T-cell lymphoma apoptosis by TRIF and NF-κB
por: Haitao Zou, et al.
Publicado: (2017) -
The velvet family of fungal regulators contains a DNA-binding domain structurally similar to NF-κB.
por: Yasar Luqman Ahmed, et al.
Publicado: (2013) -
A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice
por: Paris Roidos, et al.
Publicado: (2020) -
The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1
por: Sabrina Dietz, et al.
Publicado: (2021) -
Polydnavirus Ank proteins bind NF-κB homodimers and inhibit processing of Relish.
por: Kavita Bitra, et al.
Publicado: (2012)