Combined multiphoton imaging and biaxial tissue extension for quantitative analysis of geometric fiber organization in human reticular dermis

Abstract The geometric organization of collagen fibers in human reticular dermis and its relationship to that of elastic fibers remain unclear. The tight packing and complex intertwining of dermal collagen fibers hinder accurate analysis of fiber orientation. We hypothesized that combined multiphoto...

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Autores principales: Maho Ueda, Susumu Saito, Teruasa Murata, Tomoko Hirano, Ryoma Bise, Kenji Kabashima, Shigehiko Suzuki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d7ee556f5cd84117892e556125193208
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