A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α.
TRIM5α is a key cross-species barrier to retroviral infection, with certain TRIM5 alleles conferring increased risk of HIV-1 infection in humans. TRIM5α is best known as a species-specific restriction factor that directly inhibits the viral life cycle. Additionally, it is also a pattern-recognition...
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/d8319a2ceeae4321ab676ebe44cf7a7e |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|