A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α.
TRIM5α is a key cross-species barrier to retroviral infection, with certain TRIM5 alleles conferring increased risk of HIV-1 infection in humans. TRIM5α is best known as a species-specific restriction factor that directly inhibits the viral life cycle. Additionally, it is also a pattern-recognition...
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| Autores principales: | , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/d8319a2ceeae4321ab676ebe44cf7a7e |
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