Mapping axon initial segment structure and function by multiplexed proximity biotinylation

The axon initial segment (AIS) is a specialized location in neurons with clustered ion channels which regulates the distribution of neuronal materials. Here, the authors use proximity biotinylation to examine the AIS proteome and better define its molecular organization.

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Auteurs principaux: Hamdan Hamdan, Brian C. Lim, Tomohiro Torii, Abhijeet Joshi, Matthias Konning, Cameron Smith, Donna J. Palmer, Philip Ng, Christophe Leterrier, Juan A. Oses-Prieto, Alma L. Burlingame, Matthew N. Rasband
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/d8484c89fd574851bf45654f19bac800
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