Mapping axon initial segment structure and function by multiplexed proximity biotinylation

The axon initial segment (AIS) is a specialized location in neurons with clustered ion channels which regulates the distribution of neuronal materials. Here, the authors use proximity biotinylation to examine the AIS proteome and better define its molecular organization.

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Autores principales:	Hamdan Hamdan, Brian C. Lim, Tomohiro Torii, Abhijeet Joshi, Matthias Konning, Cameron Smith, Donna J. Palmer, Philip Ng, Christophe Leterrier, Juan A. Oses-Prieto, Alma L. Burlingame, Matthew N. Rasband
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d8484c89fd574851bf45654f19bac800
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spelling	oai:doaj.org-article:d8484c89fd574851bf45654f19bac8002021-12-02T17:32:27ZMapping axon initial segment structure and function by multiplexed proximity biotinylation10.1038/s41467-019-13658-52041-1723https://doaj.org/article/d8484c89fd574851bf45654f19bac8002020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13658-5https://doaj.org/toc/2041-1723The axon initial segment (AIS) is a specialized location in neurons with clustered ion channels which regulates the distribution of neuronal materials. Here, the authors use proximity biotinylation to examine the AIS proteome and better define its molecular organization.Hamdan HamdanBrian C. LimTomohiro ToriiAbhijeet JoshiMatthias KonningCameron SmithDonna J. PalmerPhilip NgChristophe LeterrierJuan A. Oses-PrietoAlma L. BurlingameMatthew N. RasbandNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hamdan Hamdan Brian C. Lim Tomohiro Torii Abhijeet Joshi Matthias Konning Cameron Smith Donna J. Palmer Philip Ng Christophe Leterrier Juan A. Oses-Prieto Alma L. Burlingame Matthew N. Rasband Mapping axon initial segment structure and function by multiplexed proximity biotinylation
description	The axon initial segment (AIS) is a specialized location in neurons with clustered ion channels which regulates the distribution of neuronal materials. Here, the authors use proximity biotinylation to examine the AIS proteome and better define its molecular organization.
format	article
author	Hamdan Hamdan Brian C. Lim Tomohiro Torii Abhijeet Joshi Matthias Konning Cameron Smith Donna J. Palmer Philip Ng Christophe Leterrier Juan A. Oses-Prieto Alma L. Burlingame Matthew N. Rasband
author_facet	Hamdan Hamdan Brian C. Lim Tomohiro Torii Abhijeet Joshi Matthias Konning Cameron Smith Donna J. Palmer Philip Ng Christophe Leterrier Juan A. Oses-Prieto Alma L. Burlingame Matthew N. Rasband
author_sort	Hamdan Hamdan
title	Mapping axon initial segment structure and function by multiplexed proximity biotinylation
title_short	Mapping axon initial segment structure and function by multiplexed proximity biotinylation
title_full	Mapping axon initial segment structure and function by multiplexed proximity biotinylation
title_fullStr	Mapping axon initial segment structure and function by multiplexed proximity biotinylation
title_full_unstemmed	Mapping axon initial segment structure and function by multiplexed proximity biotinylation
title_sort	mapping axon initial segment structure and function by multiplexed proximity biotinylation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d8484c89fd574851bf45654f19bac800
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Mapping axon initial segment structure and function by multiplexed proximity biotinylation

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