Inherent flexibility of CLIC6 revealed by crystallographic and solution studies

Abstract Chloride intracellular channels (CLICs) are a family of unique proteins, that were suggested to adopt both soluble and membrane-associated forms. Moreover, following this unusual metamorphic change, CLICs were shown to incorporate into membranes and mediate ion conduction in vitro, suggesti...

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Autores principales: Alisa Ferofontov, Roi Strulovich, Milit Marom, Moshe Giladi, Yoni Haitin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d8813ac4fc1b461b81311090de4a4bce
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