Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood

Inflammasome activation is linked to the aggregation of the adaptor protein ASC into a multiprotein complex, known as the ASC speck. Redistribution of cytosolic ASC to this complex has been widely used as a readout for inflammasome activation and precedes the downstream proteolytic release of the pr...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Nico Wittmann, Ann-Kathrin Behrendt, Neha Mishra, Lukas Bossaller, Almut Meyer-Bahlburg
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
Accès en ligne:https://doaj.org/article/d88e83223c05471d9d77568b3e1df41c
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!