CTD: An information-theoretic algorithm to interpret sets of metabolomic and transcriptomic perturbations in the context of graphical models.

We consider the following general family of algorithmic problems that arises in transcriptomics, metabolomics and other fields: given a weighted graph G and a subset of its nodes S, find subsets of S that show significant connectedness within G. A specific solution to this problem may be defined by...

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Auteurs principaux: Lillian R Thistlethwaite, Varduhi Petrosyan, Xiqi Li, Marcus J Miller, Sarah H Elsea, Aleksandar Milosavljevic
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/d8935c88ca1248f9bd4404aed5f9f659
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