Aqueous and pH dependent coacervation method for taste masking of paracetamol via amorphous solid dispersion formation

Abstract Taste masking of paracetamol was achieved by preparing amorphous solid dispersion (ASD) using modified coacervation method. The method is based on dissolving the drug and polymeric carrier in water adjusted to certain pH level. Then, precipitation of ASD granules is performed by gradually c...

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Autores principales: Basheer Al-kasmi, M. H. D. Bashir Alsirawan, Anant Paradkar, Abdul-Hakim Nattouf, Hind El-Zein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d89fa4cc4d8840dab3e9526388ae31af
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