Quantal Ca2+ release mediated by very few IP3 receptors that rapidly inactivate allows graded responses to IP3

Summary: Inositol 1,4,5-trisphosphate receptors (IP3Rs) are intracellular Ca2+ channels that link extracellular stimuli to Ca2+ signals. Ca2+ release from intracellular stores is “quantal”: low IP3 concentrations rapidly release a fraction of the stores. Ca2+ release then slows or terminates without...

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Autores principales: Ana M. Rossi, Andrew M. Riley, Geneviève Dupont, Taufiq Rahman, Barry V.L. Potter, Colin W. Taylor
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/d8a24df4d63f46e6850a128da1909549
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