In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer’s disease transgenic mice using synchrotron-based infrared imaging

Abstract Amyloid plaques composed of Aβ amyloid peptides and neurofibrillary tangles are a pathological hallmark of Alzheimer Disease. In situ identification of early-stage amyloid aggregates in Alzheimer’s disease is relevant for their importance as potential targets for effective drugs. Synchrotro...

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Autores principales: Núria Benseny-Cases, Elena Álvarez-Marimon, Ester Aso, Margarita Carmona, Oxana Klementieva, Dietmar Appelhans, Isidre Ferrer, Josep Cladera
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d8a5ad123a7a4b33aa19c03be9c3699c
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