Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights.
Lantibiotic synthetases are remarkable biocatalysts generating conformationally constrained peptides with a variety of biological activities by repeatedly utilizing two simple posttranslational modification reactions: dehydration of Ser/Thr residues and intramolecular addition of Cys thiols to the r...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/d8ade89d6f5344008dc28ab3ce01cc01 |
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