Monitoring of compound resting membrane potentials of cell cultures with ratiometric genetically encoded voltage indicators

Rühl et al. report the generation of ratiometric genetically encoded voltage indicators (GEVIs) and establish that they can be used in high-throughput automated imaging to measure compound membrane potential (Vm) in mammalian cells. This method is implementable with standard fluorescence microscopes...

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Auteurs principaux: Philipp Rühl, Johanna M. Langner, Jasmin Reidel, Roland Schönherr, Toshinori Hoshi, Stefan H. Heinemann
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/d8fdccc7299e4650ba56c7bdfa3b227d
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