Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw Edema Test

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw Edema Test

Marta Szandruk-Bender,1 Anna Merwid-Ląd,1 Benita Wiatrak,1 Maciej Danielewski,1 Stanisław Dzimira,2 Danuta Szkudlarek,3 Łukasz Szczukowski,4 Piotr Świątek,4 Adam Szeląg1 1Department of Pharmacology, Wroclaw Medical University, Wroc&l...

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Bibliographic Details
Main Authors: Szandruk-Bender M, Merwid-Ląd A, Wiatrak B, Danielewski M, Dzimira S, Szkudlarek D, Szczukowski Ł, Świątek P, Szeląg A
Format: article
Language:EN
Published: Dove Medical Press 2021
Subjects:
carrageenan
anti-inflammatory agents
pyrrolo[3
4-d]pyridazinone
1
3
4-oxadiazole
inflammatory mediators
toxicity
Pathology
RB1-214
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/d90f1bb5903e43d280d94fe8e9e79b5f
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