Fast and precise detection of DNA methylation with tetramethylammonium-filled nanopore

Abstract The tremendous demand for detecting methylated DNA has stimulated intensive studies on developing fast single-molecule techniques with excellent sensitivity, reliability, and selectivity. However, most of these methods cannot directly detect DNA methylation at single-molecule level, which n...

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Autores principales: Ying Wang, Yani Zhang, Yanli Guo, Xiao-feng Kang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d9155eca816146ab9618e01d64b28e49
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