An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration

Abstract Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in Sprague-Dawley r...

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Autores principales: Martha Kim, Joo-Hee Park, Hyejoong Jeong, Jinkee Hong, Woo Sung Choi, Byung-Han Lee, Choul Yong Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d926431327e14bb8845cd1c1d475fb5e
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