The Multifaceted Antibacterial Mechanisms of the Pioneering Peptide Antibiotics Tyrocidine and Gramicidin S
ABSTRACT Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S were the first commercially used antibiotics, yet it remains unclear exactly how they kill bacteria. We investigated their mode of action using a bacterial cytological profiling approach. Tyrocidines form...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2018
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Acceso en línea: | https://doaj.org/article/d9271b17950c45d6963eeb7b57386a0e |
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