The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

Abstract Regulatory T cells (Tregs) have been shown to play a protective role in glomerulonephritis (GN) and Foxp3 is a master transcription factor in Treg development. In this study, we examined the functional role and mechanisms of Foxp3 in a mouse model of accelerated anti-glomerular basement mem...

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Auteurs principaux: Chen Yang, Xiao-Ru Huang, Erik Fung, Hua-Feng Liu, Hui-Yao Lan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/d92d7c3275e042558ab6ae9924f1e18b
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