The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis
Abstract Regulatory T cells (Tregs) have been shown to play a protective role in glomerulonephritis (GN) and Foxp3 is a master transcription factor in Treg development. In this study, we examined the functional role and mechanisms of Foxp3 in a mouse model of accelerated anti-glomerular basement mem...
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Autores principales: | Chen Yang, Xiao-Ru Huang, Erik Fung, Hua-Feng Liu, Hui-Yao Lan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/d92d7c3275e042558ab6ae9924f1e18b |
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