Gains, losses and changes of function after gene duplication: study of the metallothionein family.

Metallothioneins (MT) are small proteins involved in heavy metal detoxification and protection against oxidative stress and cancer. The mammalian MT family originated through a series of duplication events which generated four major genes (MT1 to MT4). MT1 and MT2 encode for ubiquitous proteins, whi...

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Autores principales: Ana Moleirinho, João Carneiro, Rune Matthiesen, Raquel M Silva, António Amorim, Luísa Azevedo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/d9472db12e1e4d6e860b83f96873e728
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