Assessment of inactivating stop codon mutations in forty Saccharomyces cerevisiae strains: implications for [PSI] prion- mediated phenotypes.

The yeast prion [PSI(+)] has been implicated in the generation of novel phenotypes by a mechanism involving a reduction in translation fidelity causing readthrough of naturally occurring stop codons. Some [PSI(+)] associated phenotypes may also be generated due to readthrough of inactivating stop co...

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Auteurs principaux: David A Fitzpatrick, Jennifer O'Brien, Ciara Moran, Naushaba Hasin, Elaine Kenny, Paul Cormican, Amy Gates, Derek W Morris, Gary W Jones
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/d96d2abe95774a39a7b2348f7d6a2017
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