A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

ABSTRACT Obesity is a risk factor for developing severe disease following influenza virus infection; however, the comorbidity of obesity and secondary bacterial infection, a serious complication of influenza virus infections, is unknown. To fill this gap in knowledge, lean and obese C57BL/6 mice wer...

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Bibliographic Details
Main Authors: Erik A. Karlsson, Victoria A. Meliopoulos, Nicholas C. van de Velde, Lee-Ann van de Velde, Beth Mann, Geli Gao, Jason Rosch, Elaine Tuomanen, Jon McCullers, Peter Vogel, Stacey Schultz-Cherry
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Streptococcus pneumoniae
coinfection
influenza
lung infection
obesity
Microbiology
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Online Access:https://doaj.org/article/d96ed1881a754155b64ba03834a557e6
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https://doaj.org/article/d96ed1881a754155b64ba03834a557e6

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