Targeting CD38 in acute myeloid leukemia interferes with leukemia trafficking and induces phagocytosis

Abstract Targeting the interaction between leukemic cells and the microenvironment is an appealing approach to enhance the therapeutic efficacy in acute myeloid leukemia (AML). AML infiltration induces a significant release of inflammatory cytokines in the human bone marrow niche which accelerates l...

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Bibliographic Details
Main Authors: Meike Farber, Yiyang Chen, Lucas Arnold, Michael Möllmann, Eva Boog-Whiteside, Yu-An Lin, H. Christian Reinhardt, Ulrich Dührsen, Maher Hanoun
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/d97d5af41fbb4c26838feff8bdc564fe
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