Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice
Abstract Background This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including survival rate, tumor formation and tumor spec...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
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BMC
2021
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Sujets: | |
Accès en ligne: | https://doaj.org/article/d9a0a12503cf4b28be4de1b7ca1a1dd9 |
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