Inhibitory peptide of mitochondrial μ-calpain protects against photoreceptor degeneration in rhodopsin transgenic S334ter and P23H rats.
Mitochondrial μ-calpain and apoptosis-inducing factor (AIF)-dependent photoreceptor cell death has been seen in several rat and mouse models of retinitis pigmentosa (RP). Previously, we demonstrated that the specific peptide inhibitor of mitochondrial μ-calpain, Tat-µCL, protected against retinal de...
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Autores principales: | Taku Ozaki, Sei-ichi Ishiguro, Satoshi Hirano, Ayaka Baba, Tetsuro Yamashita, Hiroshi Tomita, Mitsuru Nakazawa |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/d9c9a4ab2b594670a3211839c808516b |
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