Capture of associated targets on chromatin links long-distance chromatin looping to transcriptional coordination

Chromatin architecture is a key regulator of transcriptional processes, however current methods to investigate it have technical limitations. Here, the authors describe a novel chromatin capture technique, CATCH, which can be used to identify and characterize complex genomic interaction networks.

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Auteurs principaux: Ryan J. Bourgo, Hari Singhal, Geoffrey L. Greene
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/d9d922e6f2af4de89e92707b4595c4a8
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