The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.

The PML tumor suppressor is the founding component of the multiprotein nuclear structures known as PML nuclear bodies (PML-NBs), which control several cellular functions including apoptosis and antiviral effects. The ubiquitin specific protease USP7 (also called HAUSP) is known to associate with PML...

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Auteurs principaux: Feroz Sarkari, Xueqi Wang, Tin Nguyen, Lori Frappier
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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R
Q
Accès en ligne:https://doaj.org/article/da0c9192a2914e2298198e0741c41e13
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